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GENTAUR Europe BVBA Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45 Fax 0032 16 50 90 45 This email address is being protected from spambots. You need JavaScript enabled to view it.">This email address is being protected from spambots. You need JavaScript enabled to view it. |
GENTAUR BULGARIA
53 Iskar Str. 1191 Kokalyane, Sofia
Tel 0035924682280
Fax 0035929830072
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GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50
Fax 01 43 25 01 60
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GmbH Marienbongard 20
52062 Aachen Deutschland
Tel (+49) 0241 56 00 99 68
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GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531
Fax 020 8445 9411
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GENTAUR Poland Sp. z o.o.
ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
Tel 058 710 33 44
Fax 058 710 33 48
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GENTAUR Nederland BV
Kuiper 1
5521 DG Eersel Nederland
Tel 0208-080893
Fax 0497-517897
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GENTAUR SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6, 24122 Bergamo
Tel 02 36 00 65 93
Fax 02 36 00 65 94
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GENTAUR Spain
Tel 0911876558
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Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
Phone/Fax:
(408) 780-0908
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GENPRICE Inc. invoicing/ accounting:
6017 Snell Ave, Suite 357
San Jose, CA. 96123
Serbia, Macedonia,
Montenegro, Croatia:
Tel 0035929830070
Fax 0035929830072
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GENTAUR Romania
Tel 0035929830070
Fax 0035929830072
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GENTAUR Greece
Tel 00302111768494
Fax 0032 16 50 90 45
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Other countries
Luxembourg +35220880274
Schweiz Züri +41435006251
Danmark +4569918806
Österreich +43720880899
Ceská republika Praha +420246019719
Ireland Dublin +35316526556
Norge Oslo +4721031366
Finland Helsset +358942419041
Sverige Stockholm +46852503438
Magyarország Budapest +3619980547
In Tibet, Dogs Breathe Comfortably With Less Oxygen
See Spot run. See Lassie save Timmy from a well. See Tibetan Mastiffs climb 4,500 meters above sea level on the Tibetan Plateau. The ever-so-fluffy Tibetan Mastiff, which commonly serves as a guard dog for the plateau's residents, is able to breathe comfortably at high altitudes. Like the Tibetan people, Tibetan Mastiffs have adapted to air with less oxygen.
Ya-Ping Zhang and a team of scientists examined sets of genes from 32 Tibetan Mastiffs, 20 Chinese native dogs, and 14 wolves to investigate how the Mastiffs have adjusted. They looked for variations in the DNA sequence called single-nucleotide polymorphisms (SNPs, also pronounced simply as "snips"). The scientists genotyped the SNPs in the Mastiffs and compared them to the ones in the dogs and wolves.
After finding more than 120,000 SNPs, Zhang and the scientists identified 16 genes with signals of positive selection in the Tibetan Mastiff – 12 of these genes are connected to functions in the body that would help the canine adapt to high altitudes with low oxygen levels. Several of these genes are responsible for the building of hemoglobin, which helps transport oxygen through blood, and monitoring metabolism. Oxygen is required to process consumed food into energy, so efficient metabolizing means less oxygen is used. One of the genes, EPAS1, has also been linked to helping Tibetan humans adapt to high altitudes.