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GENTAUR Europe

 GENTAUR Europe BVBA
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45 
Fax 0032 16 50 90 45
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Gentaur Bulgaria

 GENTAUR BULGARIA
53 Iskar Str. 1191 Kokalyane, Sofia
Tel 0035924682280 
Fax 0035929830072
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    GENTAUR France

     GENTAUR France SARL
    9, rue Lagrange, 75005 Paris 
    Tel 01 43 25 01 50 
    Fax 01 43 25 01 60
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    Gentaur Germany

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      GmbH Marienbongard 20
    52062 Aachen Deutschland
    Tel (+49) 0241 56 00 99 68 
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    Gentaur London

     GENTAUR Ltd. 
    Howard Frank Turnberry House 
    1404-1410 High Road 
    Whetstone London N20 9BH 
    Tel 020 3393 8531 
    Fax 020 8445 9411
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    GENTAUR Poland

     GENTAUR Poland Sp. z o.o. 

    ul. Grunwaldzka 88/A m.2

    81-771 Sopot, Poland
    Tel  058 710 33 44
    Fax 058 710 33 48 
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    GENTAUR Nederland

     GENTAUR Nederland BV
    Kuiper 1 
    5521 DG Eersel Nederland
    Tel 0208-080893 
    Fax 0497-517897
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    Gentaur Italy

     GENTAUR SRL IVA IT03841300167

    Piazza Giacomo Matteotti, 6, 24122 Bergamo
    Tel 02 36 00 65 93 
    Fax 02 36 00 65 94
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    GENTAUR Spain

     GENTAUR Spain
    Tel 0911876558
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    Genprice USA

    usa-flagGenprice Inc, Logistics
    547, Yurok Circle
    San Jose, CA 95123
    Phone/Fax: 

    (408) 780-0908 

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    GENPRICE Inc. invoicing/ accounting:
    6017 Snell Ave, Suite 357
    San Jose, CA. 96123

     

    Gentaur Serbia

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    montenegro-flagMontenegro, croatiaCroatia: 
    Tel 0035929830070 
    Fax 0035929830072
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    GENTAUR Romania

    romGENTAUR Romania

    Tel 0035929830070 
    Fax 0035929830072
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    GENTAUR Greece

    grGENTAUR Greece 

    Tel 00302111768494 
    Fax 0032 16 50 90 45

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    Other countries

    Other countries
    Luxembourg +35220880274
    Schweiz Züri +41435006251
    Danmark +4569918806
    Österreich +43720880899
    Ceská republika Praha +420246019719
    Ireland Dublin +35316526556
    Norge Oslo +4721031366
    Finland Helsset +358942419041
    Sverige Stockholm +46852503438
    Magyarország Budapest +3619980547

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    Cloned MouseScientists in Japan cloned a mouse from a drop of blood. Moving blood cells taken from the tail of the mouse donor were used to create the clone, said researchers from the center Ricken Bioresources. Some time ago the same scientists have created nearly 600 exact genetic copies of a mouse.

    Mice were cloned from different sources of donor cells, including white blood cells of the lymph nodes, bone marrow and liver. Japanese researchers studied whether the moving blood cells can be used for cloning. Their goal was to find an easy source of donor cells for cloning valuable scientifically types of laboratory mice.

    Scientists led by Atsuo Ogura of Bioresources Rikes center in Tsukuba, blood taken from the tail of a mouse donor, isolated white blood cells and used kernel cloning experiments using the same technique as for the cloning of Dolly the sheep in Edinburgh.

    The process, known as somatic cell nuclear transfer involving transfer of the nucleus from a cell in the adult body as blood cells or skin unfertilized egg, which was removed the nucleus. Scientists, whose research was published in the journal Biology of Reproduction, said that it shows for the first time that mice can be cloned using the nucleus of peripheral blood cells.

    "These cells can be used to clone immediately after isolation, without requiring euthanasia of donor" complemented researchers.

    Published in News
    Monday, 11 March 2013 15:15

    Knock-in and Knock-out Rat

    Targatt provides a complete range of gene targeting services in rats to generate transgenic knock-in and knock-out rat models.

    Rats are more versatile research model animals than mice since they are physiologically more similar to humans. The recent isolation of rat embryonic stem (ES) cells opened the doors to the generation of transgenic rats and we are proud to be one of the first providers of an all-inclusive transgenic rat generation service. Our competence in gene-targeting vector design coupled with our expertise in culturing rat ES cells allows us to offer a high-quality customized service for the generation of transgenic knock-in and knock-out rats.

    Using our proprietary germline competent rat ES cell lines we can create your customized transgenic rat model, including

    • - Constitutive knockin/out
    • - Conditional knockin/out
    • - Inducible knockin/out
    • - Point mutations
    • - Random integration
    • - Insertion of reporter genes
    • - Humanized rat models
    • - Disease rat models
    • knock-in-knock-out-mouse-targatt-1

     

    We take great pride in offering you the highest level of service and we are committed to ensuring the success of your transgenic rat project. Our service includes an initial project assessment based on your model requirements. A dedicated PhD level project manager will discuss available gene targeting vector design strategies and will update you continuously throughout the project.

    We provide the most flexible customized service options whether you’d like us to do all the work or are on a tight budget and prefer doing some steps yourself.

     Full Transgenic Rat Generation Service Includes:

    • - Gene targeting vector design, construction and sequencing
    • - Rat ES cell targeting, screening and expansion of positive rat ES cell clones
    • - Karyotyping of targeted rat ES cells
    • - Chimera production via blastcyst injection
    • - Chimera breeding for germline transmission
    • - Genotyping of offspring
    • - Transfer of heterozygous targeted rats to the customer
    • - Optional: breeding to generate homozygous rats

     

    All our animals are housed in a facility that is accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International, has an Assurance on file with the Office of Laboratory Animal Welfare (OLAW), and is a registered research facility with the U.S. Department of Agriculture.

    knock-in-knock-out-mouse-targatt-2

    We also offer Knock-in/Knock-out Mouse and Transgenic Mouse (Random Insertion) services. For more information please contact us.

     

    Published in Targatt services