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 GENTAUR Europe BVBAVoortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45 Fax 0032 16 50 90 45 This email address is being protected from spambots. You need JavaScript enabled to view it.">This email address is being protected from spambots. You need JavaScript enabled to view it. |
GENTAUR BULGARIA
53 Iskar Str. 1191 Kokalyane, Sofia
Tel 0035924682280
Fax 0035929830072
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GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50
Fax 01 43 25 01 60
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GmbH Marienbongard 20
52062 Aachen Deutschland
Tel (+49) 0241 56 00 99 68
Fax (+49) 0241 56 00 47 88 This email address is being protected from spambots. You need JavaScript enabled to view it." style="font-family: Arial, Tahoma, Verdana, Helvetica; line-height: 15.59375px; ">
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GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531
Fax 020 8445 9411
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GENTAUR Poland Sp. z o.o.
ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
Tel 058 710 33 44
Fax 058 710 33 48
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GENTAUR Nederland BV
Kuiper 1
5521 DG Eersel Nederland
Tel 0208-080893
Fax 0497-517897
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GENTAUR SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6, 24122 Bergamo
Tel 02 36 00 65 93
Fax 02 36 00 65 94
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GENTAUR Spain
Tel 0911876558
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Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
Phone/Fax:
(408) 780-0908
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GENPRICE Inc. invoicing/ accounting:
6017 Snell Ave, Suite 357
San Jose, CA. 96123
Serbia, 
Macedonia,
Montenegro, 
Croatia:
Tel 0035929830070
Fax 0035929830072
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GENTAUR Romania
Tel 0035929830070
Fax 0035929830072
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GENTAUR Greece
Tel 00302111768494
Fax 0032 16 50 90 45
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Other countries
Luxembourg +35220880274
Schweiz Züri +41435006251
Danmark +4569918806
Österreich +43720880899
Ceská republika Praha +420246019719
Ireland Dublin +35316526556
Norge Oslo +4721031366
Finland Helsset +358942419041
Sverige Stockholm +46852503438
Magyarország Budapest +3619980547
New antibiotics are developed based on peptides
A new study published in the Proceedings of the National Academy of Sciences USA, PNAS, conducted by researchers at the Ruhr University in Bochum, shows how peptides can be designed so that attack bacterial cells.
Researchers believe that the disposal of pathogenic bacteria could be done without harming human cells.
Moreover, this type of therapy would reduce the risk of resistance that developed most pathogens to previously applied drugs.
Previous studies have already shown that many antimicrobial peptides interact with cell membranes of the bacteria and thus perform its microbicidal effect.
RUB team has turned his attention to the study of a peptide called MP196, which is a group of very small positively charged peptides consisting of four to ten amino acids.
From previous studies it is known that the MP196 can cope with a variety of bacteria including some that are multi - drug-resistant, but it is unclear exactly how this process is carried out.
Researchers have demonstrated that prevents MP196 proteins in the cell membrane of the bacteria and thereby distort two key cellular processes: cell wall biosynthesis and cell breathing.
Through disruption of cell wall biosynthesis, the peptide interferes with the integrity of the bacterial cell, and by interfering with the cellular respiration, distorts the production of ATP, the molecule that stores the energy used by the cell.
Scientists are confident that the MP196 offers a starting point for developing new drugs that attack specific classes of bacteria without harming human cells, but to be confirmed in their findings need to go a long way.
The study is part of the development of innovative antibiotics.
To solve new drugs, federal authorities need detailed information about the procedure and the effects of drugs on both pathogens and on human cells.
