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GENTAUR Europe

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Voortstraat 49, 1910 Kampenhout BELGIUM
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 GENTAUR BULGARIA
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    Displaying items by tag: Drugs

    gentaur-lymphoma-inhibitor-peptide-e.coli-mapk-tissue-identify-cytokine-activated-lymphomaSwiss scientists have developed a new protein structure, which may improve the efficacy of drugs. New synthetic amino acid can be used to create entirely new drugs.
     
    Development of new and effective drugs is a feat for many researchers. Until now, most drugs based on the basis of amino acid obtained naturally. These include insulin hormone, vancomycin and the like.
     
    There are a variety of peptides and proteins, but only 20 different amino acids. They form a unique structure when they are "stacked" together. The synthetic structure created by the Swiss researcher is similar to that of cysteine ​​- sulfuric amino acid. Synthetic however is significantly more efficient.
     
    Disease attack appear more and more people. It takes more effective drugs that can handle the increasing resistance. Like the natural chemical structures may create such a new and improved treatment of various diseases.

    Cysteine ​​can form a bridge to the cysteine ​​amino acid found in it, thereby creating 3D structure. The new amino acid, however, can form two bridges, when coupled with other similar amino acid cysteine​​.
     
    Laboratory tests revealed that the newly synthesized amino acid is eight times more efficient and fight disease by 40-fold higher speed in comparison with a naturally occurring amino acid cysteine.

    Published in News

    targatt-pcr premix-antibodies-elisa-cell-cultureAccording to a report published in the Annals of Oncology, women with Herr-2 positive breast cancer who received trastuzumab as adjuvant therapy are at significantly increased risk of metastases in the central nervous system as a first recurrence of the tumor.

    According to Dr. Erin Olson, a neurologist at Ohio State University and author of the study, trastuzumab significantly reduced the risk of recurrence, but clinicians should be aware that it increases the risk of them occur in the nervous system. Physicians should carefully monitor patients for neurologic symptoms.

    It is suggested that the nervous system is the "refuge" for micro metastatic tumors because trastuzumab does not cross the blood-brain barrier or because tumor cells that do not overexpress Herr-2 receptor migrate more easily into the brain.

    In previous studies, Dr. Olson and her team showed that anti Herr-2 targeted therapies increase the frequency of brain metastases. This spurred her to investigate the relationship between brain metastases and trastuzumab. The team analyzed four Phase III clinical trials with a total of 9,020 participants.

    Since 4921 women receiving trastuzumab, 125 relapse in the breast (incidence of 2.56%). Of 4099 women who received trastuzumab, 78 relapse of the tumor in the brain (1.94%). In patients treated with trastuzumab treatment brain metastases / total metastases is 16.94 / 100, while those treated with other adjuvant is 8.33 / 100.

    Published in News