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Monday, 11 March 2013 15:33

Stem Cell Generation

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We have successfully derived many induced pluripotent stem cell (iPSC) lines from patient specific fibroblasts.

We have three methods for iPSC generation: mRNA, episomal (both genomic footprint-free), or retroviral.

Genomic footprint-free Induced Pluripotent Stem Cell (IPSC) Generation Service:

  • - No genomic footprint - the non-integrating system is safe in drug discovery and cell therapy applications.
  • - Two methods available: Episomal DNA vectors containing the reprogramming factors or mRNA.
  • - High reprogramming efficiency (0.2%-0.5%).
  • - The reprogramming vectors/mRNA are removed naturally during the cell cycle.
  • - Safe to handle - no viral particles.

 

  • stemcell-targatt-knockin-knockout-mouse-1
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