GENTAUR Europe BVBA
Genprice Inc, Logistics
Serbia, 
Macedonia, 
Montenegro, 
Croatia: 
GENTAUR Romania
GENTAUR Greece 
Based on our proprietary TARGATT Technology for site-specific knock-in mouse generation, we developed a TARGATT system specifically for introducing gene(s) of interest into mammalian cell lines. The unique advantage of this system is that any gene of interest can be inserted efficiently into a defined, transcriptionally-active locus with high gene expression in a single copy fashion.
TARGATT Features:
- Site-specific insertion of any gene
- High integration efficiency
- Single-copy integration
- Stable expression
- Fast: get your transgenic cell line in 3 months!
Targatt proprietary TARGATT Technology enables highly efficient site-specific gene integration in mammalian cells and animals. This technology uses PhiC31 integrase to insert any gene of interest into a specific docking site that was pre-engineered into an intergenic and transcriptionally active genomic locus. Our TARGATT Technology improves several aspects in the generation of transgenic cell lines and animals:
- High integration efficiency mediated by PhiC31 integrase reduces time and cost
- Site-specific integration at a pre-selected genomic locus eliminates position effect and ensures high expression levels of the transgene
- Integration at intergenic region ensures that no internal genes are interrupted
- Single copy gene integration eliminates repeat-induced gene silencing and genomic instability
- Site-specific integration allows a precise comparison of the effects of the transgenes among different lines.
TARGATT Technology can be utilized for a variety of applications including reporter gene expression, gene knockdown and disease models.
