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Wednesday, 06 March 2013 11:03

TARGATT Knockin Mice - Stem Cells Products

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targatt-stemcells-knockin-mouse-1TARGATT Embryos

Using our novel TARGATT system, a gene of interest can be specifically inserted at a well-characterized, transcriptionally-active locus in the mouse genome with guaranteed transgene expression. Tissue-specific and / or ubiquitous expression options are available.

 

Advantages of TARGATT technology:

  1. Site-specific gene integration at a transcriptionally-active locus ensures high-level gene expression.
  2. Integration happens at an intergenic region; no internal genes are disrupted.
  3. The integrase system catalyzes a unidirectional integration event and results in a high efficiency in producing transgenic mice.
  4. Gene integration at the same locus allows a precise comparison of the transgenics from one line to another.

 

targatt-stemcells-knockin-mouse-2TARGATT Kits

TARGATT Supporting Materials

 

 

Mouse Embryonic Fibroblasts (MEF)

targatt-stemcells-knockin-mouse-3  CF-1
  Neo-resistant
  DR4
  SNL (STO feeder cells)

SNL (STO feeder cells)

 

Cell Culture Products

  Germline-tested & ESC-qualified FBS
  Specialty Media
  Basal Media (DMEM)
  Stem Cell Growth and Differentiation Factors
  ASC Small Molecules
  3D Culture and Expansion System

Reprogramming

targatt-stemcells-knockin-mouse-4

targatt-stemcells-knockin-mouse-5

 

 

 

 

 

 

 

ESC/iPSC Characterization

  Pluripotency Protein Markers                   Stem Cell Gene Array
 targatt-stemcells-knockin-mouse-6    targatt-stemcells-knockin-mouse-7

●  Pluripotency mRNA Markers
●  Components

 

ESC/iPSC Differentiation

  Neural Differentiation
  Dendritic Cell (DC) Generation

ES/iPS Cell Lines

Mouse ES Cell Lines                                 Human iPS Cells

targatt-stemcells-knockin-mouse-8   targatt-stemcells-knockin-mouse-9

Cell Depository

Primary Cell, cDNA, RNA (Normal)

targatt-stemcells-knockin-mouse-10  Endocrine
  Neural
  Pulmonary
  Digestive
  Urinary
  Reproductive
  Skeletal Muscle
  Hematopoietic
  Integumentary
  Cardiovascular
  Miscellaneous

Primary Cell, cDNA, RNA (Disease)

  Blood Disorders
  Neurological Disorders
  Degenerative Disorders
  Metabolic Disorders
  Cardiovascular Disorders
  Congenital Disorders
  Endocrine Disorders
  Autoimmune Disorders
  Genetic Disorders
  Muscular Disorders
  Oncogenic Disorders

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Read more about Targatt gene modification here

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