Fungal molecule allows to realize the effect of the antibiotic to achieve the cure. It can be the key to suppression of resistance to antibiotics, according to scientists from the University of McMaster, Canada.
The emergence of antibiotic resistance, role playing gene known as NDM-1. The World Health Organization recognizes it as a global threat to human health due to its resistance to some of the most powerful class of antibiotics known as carbapenems.
Despite his frightening presence in many bacterial strains, NDM-1 is found in the most common bacteria among people - Escherichia coli - bacteria that causes most infections of the bladder and kidneys. Without antibiotics to "fight" with NDM-1, doctors are helpless.
The carbapenem class of drugs are very similar to penicillin, which means that they are used in a variety of unique situations. Researchers worse is that NDM-1 affects many organisms which themselves cause all sorts of "challenging" conditions and now have multi-drug resistance.
Before fungal molecule to be detected in the soil in Nova Scotia, Canada, researchers found that NDM-1 requires zinc to "grow." The challenge in them was to find a way to remove zinc safely and without causing the appearance of side effects for the patient. With the discovery of the molecule, known as AMA, this extraction becomes possible.
During the laboratory studies, the experts found that it is really effective and allows the antibiotic to act in order to achieve cure. But there is still much work to researchers, pending the development of a "global" solution.
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Green light in the battle against antibiotic resistance
