Incitement of tumor cells devours itself would probably be one of the best decision on the treatment of large numbers of tumor diseases.
In a new study, researchers found that a combination of certain medications can cause the cancer cells to "cannibalism", without damaging healthy tissue. This type of treatment has demonstrated efficacy in tumors in the colon, liver, lung, breast, brain and kidneys.
Researchers are trying to determine whether co-administration of drugs sorafenib and regorafenib can be combined with so-called PI3K/AKT inhibitors to achieve better effect.
Andrew Poklepovic who is co-author of this work, says that despite the need for further research, the results so far are promising. Scientists are encouraged by the fact that the drugs used have already been approved by the FDA to treat certain types of tumors or are currently undergoing trials and pending approval.
The medicaments sorafenib and regorafenib influence the growth of tumor cells by blocking the release of enzymes - kinases that play a decisive role in the spread of cancer cells.
Newfound combination drugs enhances this effect, as it adds a new class of kinases inhobitori - PI3K/AKT inhibitors. Thus, many of the tumor cells "starve", limiting tumor growth.